Based on the passage, which of the following conditions would most likely be aggravated by drugs that increase beta-adrenergic receptor activity? a) the common cold b ) diabetes mellitusc ) poor night visiond) lactic acid accumulation

B ) Diabetes mellitus

Explanation:

   Adrenergic receptors were initially divided into two broad categories, α and β .  β-adrenergic receptors are present in different cells, acting in a variety of functions, including hormone release modulation, metabolic control and cardiovascular regulation.

   Stimulation of β-adrenergic receptors in Langerhans islets promotes increased blood glucose in humans, so that β2-adrenergic agonists are used to treat hypoglycemia. In adipocytes, it has been shown that β3 receptors act on leptin release. Moreover, the balance between lipogenesis and lipolysis is associated with stimulation of α and β-adrenergic receptors, respectively.

    β-adrenergic agonists (drugs that increase β-adrenergic receptors activity) activate specific membrane receptors of muscle fibers and adipocytes, modifying cellular metabolism of muscle and adipose tissues.  They can cause hyperglicemia, which aggravate the diabetes problem.

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