What historical event in medieval history led to european interest in trade with the middle east?
a. the european crusades
b. the italian renaissance
c. the birth of the prophet mohammad
d. the birth of jesus in bethlehem

The historical event in the medieval period that led to European interest in trade with the Middle East was the European Crusades. The correct option among all the options that are given in the question is the first option or option "A". I hope that the answer has come to your help.