What is limited by a cells surface-are-to-volume ratio

The important point is that the surface area to the volume ratio gets smaller as the cell gets larger. Thus, if the cell grows beyond a certain limit, not enough material will be able to cross the membrane fast enough to accommodate the increased cellular volume. ... That is why cells are so small.

the proximity of water was an advantage to western europe and its culture was able to flourish as a result. trade and travel by sea were easier and safer in historical times.

1. there are no mountains to protect it from the sea

2. and its has wet cool summers and wet, mild winters.