Which sentence contains correctly placed commas? O She was, however, too tired to make the trip.
O It is up to you to finish Jane.
The candidate for mayor promised to decrease crime, and to generate more jobs.

She was, however, too tired to make the trip.

Explanation:

The second option, as is, means that the speaker is talking to someone other than Jane and telling them that it's up to them to finish her. It needs a comma after "finish" to represent the speaker addressing Jane. "It is up to you to finish, Jane."

The third option has a comma it doesn't need. When there are only two items listed, no comma is needed. Three or more need a comma.