What does "note" mean in this passage?

Vvnici prece di evidence would best support teason #to the history of using animals for research extends asfar back as 322 bce, when early greek physician-scientists, such as aristotle and erasistratus,performed various experiments on living animals.0 animal research played an essential role in thedevelopment of herceptin and tamoxifen, twomedications that have already saved the lives ofthousands of women who have been diagnosed withbreast cancer.even those who believe in testing on animals when it isnecessary for vital medical research practice what isknown as "the 3 rs"-reduction, refinement, andreplacement to reduce the number of animals usedfor testingbiologists believe that chimpanzees share at least 98.4percent of the same dna as humans and gorillas shareat least 97 percent, making primates a popular andlikely choice for the testing of products intended for humans

Plzzz me needs a hyphen or no hyphen 1. laura, a friendly little girl, says hello to everyone she passes 2. my uncle is well known jazz musician 3. our school's winning football record is welll known 4. the angry looking woman was having a heated discussion with the store manager.

Which quotation best expresses a major theme of this speech? "i saw my evil day at hand. the sun rose dim on us in theo morning, and at night is sunk in a dark cloud, and looked likea ball of fire.""i am much grieved, for i expected, if i did not defeat you, too hold out much longer, and give you more trouble before ! surrendered."m"we went to our great father. we were encouraged. hiso great council gave us fair words and big promises, but wegot no satisfaction.".**we told them to let us alone; but they followed on andbeset our paths, and they coiled themselves among us likethe snake."