What happened and who was involved in the Story "An American Plague"

What point was thomas paine trying to make by relating this antidote

Read the passage. when mother’s fever persisted for a week, father summoned our family doctor. dr. blakemore applied leeches to mother’s skin in hopes of reducing the amount of blood in her body. despite the doctor’s efforts, she languished in bed for three more days before her appetite returned and she requested a thin broth. our dear cook, mrs. davis, prepared the broth and delivered it to my mother directly, eager to ease her discomfort. what can readers infer about the time period of the passage?

Atheater director has decided that an all-female cast will perform macbeth, which has both male and female characters. which feature of the play would change the most?