Maria Isabel sees Enrique change. His mouth becomes sweaty and sticky. He is jumpy and nervous. His eyes grow red. Sometimes they are glassy, half-closed. Other times he looks drunk. If she asks a question, the response is delayed. His temper is quick. Often he grows quiet, sleepy and distant. Other times he becomes hysterical and insulting. Sometimes he hallucinates that someone is chasing him. What has caused this strange behavior in Enrique?