In areas with dark soil color, the frequency of the MC1R allele that causes dark fur (allele 2) is high in the mouse population. For example, the frequency of MC1R allele 2 in the Lava (West) population is approximately 0.90. The opposite pattern is true in areas with light soil color. For example, the frequency of the MC1R allele 2 in the Tule Well population is approximately 0.05. These data fit the expected pattern if mice with dark fur survive better and leave relatively more offspring on dark soils and vice versa for mice on light soils. The evidence suggests that dark fur color is an adaptation for mice in dark-colored backgrounds, as both the frequency of the trait and the allele that causes the trait has changed. These data also support the idea that selection depends on environmental context, as dark mice were favored in some environments but not in others.

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