Which evidence from "Marie Curie and the Discovery of Radioactivity" best supports the idea that Marie Curie was doggedly determined when it came to seeking out knowledge?

A. "Day after day, Marie experimented with uranium under all kinds of conditions: dry and wet, powdered and solid; pure and mixed with other elements."

B. "But Marie, although still a student, had already shown that she possessed the most important quality of a successful scientist. When it came to the search for knowledge, she never gave up.

C. "Days, she worked teaching children, saving her rubles to send her older sister to medical school in the city of intellectual freedom--Paris, France."

D. "She would go on to win a second Nobel Prize, in chemistry, making her the first person ever to be awarded the Nobel Prize twice."