Which of the statements about enzymes are true? Generally, an enzyme is specific for a particular substrate. For example, thrombin catalyzes the hydrolysis of the peptide bond between Arg and Gly.

A substrate must bind to the active site before catalysis can occur.

An enzyme yields a specific product, whereas a nonbiological catalyst may produce more than one product with the occurance of side reactions.

Catalysis occurs at the active site, which usually consists of a crevice on the surface of the enzyme.

Nonbiological catalysts and enzymes tend to have a similar degree of reaction specificity.