Chemistry, 04.08.2021 15:30 darianhaynes
Arrange the sequence of reactions that occur in the conversion of pyruvate to acetyl-CoA in the correct order: The anion of the hydroxyethyl group attacks one sulfur of the disulfide in lipoic acid, and the resulting intermediate is oxidized to an acetyl thioester. FAD is reduced to FADH2, while the two thiols of reduced lipoic acid are oxidized back to a disulfide. FADH2 is oxidized by NAD producing NADH. Nucleophilic addition of thiamine pyrophosphate to pyruvate to yield hydroxyethyl-TPP and CO2. The acyl thioester derived from lipoic acid
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