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Chemistry, 08.04.2021 23:40 pennygillbert

Compound A has potent antifungal activity in a cell-free system but has poor activity in mice. (a) Write the equation for the chemical equilibrium of compound A (pKa1 ~10) in an aqueous medium at physiological pH (~ 7.2). (b) Explain why compound A is not effective in mice based on the equilibrium in (a). (c) Explain why compound B could be more effective in mice than compound A

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