Pls give a detailed explanation about what are enzyme mutations

Enzyme mutations can lead to serious or fatal human disorders and are the consequence of inherited abnormalities in the affected individual's DNA. The mutation may be at a specific position in an enzyme encoded by a mutated gene, just like a single abnormal amino acid residue.

Explanation:

Mutations in enzymes can lead to serious or fatal disorders in humans and are the consequence of inherited abnormalities in the DNA of the affected individual. The mutation may be just as a single abnormal amino acid residue at a specific position in an enzyme encoded by a mutated gene.

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explanation: