Chemistry, 22.12.2020 22:10 yachtboy1917
Widely used anti-inflammatory drug, Ibuprofen has a pKa value of 4.43. Stomach contents have pH range of 1.5-3.5, and small intestine has pH range of 6-7. Make an assumption, that the pH of stomach is 2.0 and the pH of small intestine is 7.0 Calculate the ratio between charged ibuprofen/uncharged ibuprofen at each digestive organ in the order of stomach and small intestine, and determine in which digestive organ most ibuprofen gets absorbed.
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Widely used anti-inflammatory drug, Ibuprofen has a pKa value of 4.43. Stomach contents have pH rang...
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