4.the phenol group of morphine is important in binding morphine to opioid receptors and causing analgesia. codeine has the same structure as morphine but the phenol group is masked as a methyl ether. as a result, codeine binds poorly to opioid receptors and should show no analgesic activity. however, when it is taken in vivo, it shows useful analgesic properties. explain how this might occur.

Conversion of codeine into morphine in the liver by CYP2D6.

Explanation:

Morphine is a chemical compound that is used as medication for the treatment of pain. The medication has the chemical formula of C₁₇H₁₉NO₃, Molar mass of 285.34 g/mol, Melting point of 255 °C and the Boiling point of 254 °C.

Just like it is given in the question above that is " the phenol group of morphine is important in binding morphine to opioid receptors and causing analgesia".

MAIN ANSWER:

So, when one uses Codeine, there is going to be the transformation when it gets to the liver that is the Codeine will be turned to a morphine through the help of the enzyme known as CYP2D6.

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