Many metabolites are maintained at steady state concentrations that are far from equilibrium. A comparison K'_eq and Q, the mass-action ratio, can determine whether a metabolic reaction is far from equilibrium. Calculate K'_eq for this reaction at T= 25.0 degree C delta G degree ' = -14.2 kj/mol Calculate the mass-action ratio. Q, from the approximate physiological concentrations for rat heart tissue shown at the right. Select the true statements about the PFK-1 reaction The PFK-1 reaction in heart tissue does not reach equilibrium. In heart tissue, the PFK-1 products are more abundant than reactants. In heart tissue, the PFK-1 reaction will be driven toward product formation. Under standard conditions, the PFK-1 reaction reaches equilibrium when the concentrations_of all products and reactants are equal.