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Chemistry, 17.06.2020 05:57 mmaglaya1

A total synthes's of the marine natural product aldingenin C In the laboratory resuited in a significant revision of its proposed structure. The synthesis involved the conversion of compound 1 to compound 2, which is an Intramo lecular SN2-type process. Ths substitution reaction involves a very poor leaving group, but the reaction is nevertheless favorable, because it involves opening of the strained three-membered ring (called an epoxide). The relief of ring strain can be a powerful driving force for reactions. Draw a mechanism for this reaction. Include lone pairs and formal charge in CH2.

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