As an approximation, we can assume that proteins exist either in the native (or physiologically functioning) state or the denatured state. The standard molar enthalpy and entropy of the denaturation of a certain protein are 545 kJ·mol−1 and 1.55 kJ·K−1·mol−1, respectively. Comment on the signs and magnitudes of these quantities.

Reaction is spontaneous at high temperature and nonspontaneous at low temperature

Explanation:

Given:

Enthalpy change

Entropy change

From the formula of change in free energy,

But for spontaneous process the values of quantities are given below

For spontaneous process value of is negative

For nonspontaneous process value of is positive

Here values of and are positive, so reaction is spontaneous at

high temperature and nonspontaneous at low temperature