Instrumental methods need only a microscopic sample to return an accurate result. why is this so?

Instrumental methods of analysis rely on machines.The visualization of single molecules, single biological cells, biological tissues and nanomaterials is very important and attractive approach in analytical science.
There are several different types of instrumental analysis. Some are suitable for detecting and identifying elements, while others are better suited to compounds. In general, instrumental methods of analysis are:
-Fast
-Accurate (they reliably identify elements and compounds)
-Sensitive (they can detect very small amounts of a substance in a small amount of sample)

Idon't know hope someone you

Ithink that the use of creativity in the sciences entails that one produce something out of nothing or from another thing. with this, i think that the he wrote down his results as four parts of the atomic theory is the manifestation of the  creativity of john dalton.