The instructions on the tpa vials read to reconstitute with 50 ml of sterile water to make a total of 50 mg/50 ml (1 mg/ml). the hospital protocol is to infuse 0.9 mg/kg over 60 minutes with 10% of the dose given as a bolus over 1 minute. n. t. weighs 143 pounds. what is the amount of the bolus dose, in both milligrams and milliliters, that you will administer in the first minute? what is the amount of the remaining dose that you will need to administer?

regulation of gene expression. gene expression can be regulated by various cellular processes with the aim to control the amount and nature of the expressed genes. these regulatory proteins bind to dna and send signals that indirectly control the rate of gene expression

explanation:

interphase

the period of cell growth when the cell synthesizes new molecules and organelles. the cell is not dividing and it constitutes the majority of the time spent in the cell cycle

prophase

changes occur in the nucleus and cytoplasm. the chromatin condenses to form structures (sister chromatids) visible with a light microscope and the mitotic spindle begins to form, but the nucleus is still in tact

prometaphase

the nuclear envelope fragments and the spindle microtubules attach to the kinetochores of the sister chromatids

metaphase

all the cell's duplicated chromosomes are lined up at an imaginary plane equidistant between the poles of the mitotic spindle

anaphase

begins when sister chromatids separate from each other and ending when a complete set of daughter chromosomes arrives at each of the two poles of the cell

telophase

the daughter nuclei form at the two poles of a cell

cytokinesis

the division of a cytoplasm to form two separate daughter cells. usually occurs during telophase during mitosis. this and mitosis make up to mitotic (m) phase of the cell cycle