Arthropods invaded land about 100 million years before vertebrates. this fact most clearly implies that

The answer is arthropods have had more time to co-evolve with land plants than have vertebrates. Analysis of genes shows that their sequences are quite similar, and these sequences differ from those of the lophotrochozoans and deuterostomes.  Between the annelids and arthropods will probably be viewed, in retrospect, as an instance of an evolutionary relationship that modern scientists had ʺset in stone, ʺ now having crumbled.

i believe the answer is pupils are unequal and non-reactive

the pupil of both eyes has different size, so you could say the pupil is unequal. pupil has muscle that makes it able to constrict itself according to the light intensity. when the doctor direct their flashlight to the eye, pupil should be constrict to reduce the light intensity. if the pupil doesn't change their diameter, it is called unresponsive.