What are the main differences between asexual reproduction and sexual reproduction? asexual reproduction requires two parents and produces non-identical offspring, while sexual reproduction requires only one parent and produces identical offspring. asexual reproduction requires two parents and produces identical offspring, while sexual reproduction requires only one parent and produces non-identical offspring. asexual reproduction requires only one parent and produces identical offspring, while sexual reproduction requires two parents and produces non-identical offspring. asexual reproduction requires only one parent and produces non-identical offspring, while sexual reproduction requires two parents and produces identical offspring.