"drugs produce a biological or psychological dependence in the user so that withdrawal from them leads to a craving for the drug that, in some cases, may be nearly irresistible."

The answer is: Addictive drugs produce a biological or psychological dependence in the user so that withdrawal from them leads to a craving for the drug that, in some cases, may be nearly irresistible.

Explanation:

These drugs create a constant stimuli in the brain in places responsible for the pleasure and stimuli response. The constant use of these drugs create new pathways in the brain and alterations of the common function of neurons.  As the amount of "feel good hormones" increases over time it generates a tolerance threshold that is pushed back constantly causing the anxiety of "wanting more".

hydroxyl -oh

alcohols, always polar, can form hydrogen bonds with h2o molecules

carboxyl -cooh  

cargoxylic acids, has acidic properties which is a source of hydrogen ions, found in cells in ionized for with a charge of oh-1

carbonyl > co

ketone if within skeleton, aldehyde if group is at the end of skeleton, k & a may be structural isomers, it determines 2 sugars (ketose & aldose)

amino -nh2

amines, acts as a base, it can pick up h+ ions from surrounding solution, ionized with charge of 1+

methyl ch2

addition to rna/dna affects and gene expression

phosphate -opo3 ²⁻

organic phosphates, contributes to negative charge to, molecule that it is a part of, and potential to react with h20

sulfhydryl -sh

thiols, cross-linking stabilize the protein, and it is structure

i dont know this but ask your teacher for !