Which cell technology was made possible by the development of micromanipulation tools

One of the cell technologies that was made possible by micromanipulation tools is reproductive cloning.

Reproductive cloning is a form of artificial reproduction using the cloning technique. It is distinguished from therapeutic cloning or, more properly, cloning for therapeutic purposes.

There are two cloning methods that could be considered for human reproduction: cloning by cleavage of a blastocyst, and cloning by transfer of a cell nucleus into an enucleated ovum.