During an allergic response, histamines are released by mast cells. these histamines bind to receptors on cells in the local environment only

A mast cell is a type of white blood cell, a part of immune system. They produce mediators like histamine. They have role in initiation of allergic immune response. Histamine increses the permeablity of capillaries to make the while blood cells engage the pathogens invaded.

C) they are specialized meaning they are designed to do different things