Genetic disorders can result when sister chromatids fail to separate properly. during which phase is this problem most likely to occur?

I’m doing some practice exam questions for biology, and i’m not sure how to do these 3 parts to the question.

Ry was studying two populations of the same species of lizards. one population lived on an island and the other lived on the mainland. both populations were affected by a hurricane that hit the island and the mainland with equal force. a year later, henry was testing the gene frequency and saw a decrease in genetic variation in the island species, but not in the mainland species. which best describes a conclusion he might have reached? gene flow greatly affects small populations, but large populations can recover. genetic drift greatly affects small populations, but large populations can recover. gene flow greatly affects large populations, but small populations can recover. genetic drift greatly affects large populations, but small populations can recover.

Cold case files recently began re-investigating an old murder case. the murder took place in the park; a young man, james, was hit over the head with a brick and killed. police suspected the jealous former boyfriend of james' wife, karen. whoever killed james may have washed their hands in a near-by bird bath as detectives found blood in the bird bath. since the murder took place before dna fingerprinting was available, the suspected killer, ronnie, went free. detectives are now reviewing the blood evidence using dna fingerprinting. based on the dna fingerprints of all possible suspects, who is james' killer?