Before endosymbiosis could occur, what must have been present?.

"1. it should be, it has been for about 20 years, and it's really not much different in the end than breeding animals to have particular traits. there are always concerns about genetically engineered animals/plants affecting the environment in unexpected negative ways, but i can't think of an example where the fears didn't turn out to be baseless.  

first, as you point out, it would be a great advance in pharmacology, to be able to tailor drugs and their doses to me. the pros involve better medical treatment. the cons involve privacy issues like insurance companies denying coverage to people with genetic risk factors. looking at dna markers wouldn't affect the frequency of genetic diseases, but it would allow detection of them earlier. and ok, actually i suppose that if people used this information to avoid having children with genetic diseases, some might decrease in frequency."

answer: ice crystals in air

the water from the water body or another source of water gets evaporated as water vapor as an effect of heat on water. these water vapor rises in the upper layers of the earth atmosphere under high atmospheric pressure. the atmospheric pressure of these water molecules starts to decrease due to the effect of cold air. the invisible water vapor condenses into visible water droplets and ice crystals.these ice crystals and water droplets being less denser than the surrounding air floats on air as clouds.

for a different answer set the answer would be because the oxygen in the water had depleted (apex)