ADH (Anti-diuretic hormone) is important in maintaining homeostasis in mammals. ADH is released from hypothalamus in response to high tissue osmolarity (=less water in blood). In response to ADH, the collecting duct and distal tubule in the kidney become more permeable to water, which increases water reabsorption into capillaries. The amount of hormone released is controlled by a negative feedback loop. Based on the model presented, what is the relationship between ADH release, osmolarity and production of urine? *
A. As tissue osmolarity rises, more ADH is released, causing less water to be excreted as urine
B. As tissue osmolarity rises, less ADH is released, causing less water to be excreted as urine
C. As tissue osmolarity rises, more ADH is released, causing more water to be excreted as urine
D. As tissue osmolarity rises, less ADH is released, causing more water to be excreted as urine
E. Two of the above