Can all genetic mutations be observed with a karyotype explain

Which of the following matches the organisms described with the correct domain? a. archaea--multicellular, eukaryotic organisms that do not have cell walls b. eukarya--single-celled and multicellular organisms, with a defined nucleus and a variety of nutritional sources c. bacteria--unicellular, eukaryotic organisms with cell walls that do not contain peptidoglycan d. bacteria--unicellular, eukaryotic organisms that always lack cell walls