Biology, 31.08.2021 16:50 chanthonymjones
CFTR is present in many other types of epithelial cells, including in the lung and in the pancreas. Cholera does not typically affect these tissues, since infection occurs in the gut, and cholera toxin does not move into the bloodstream. However, some people have a mutation in CFTR that decreases its activity, and thus reduces the release of chloride ions from the cytosol of epithelial cells into the lumen of these organs. Which of the following are the most likely consequences of such CFTR mutations?
a. no change in fluid secretion from the tissues where CFTR is expressed
b. decreased fluid secretion from the tissues where CFTR is expressed
c. increased fluid secretion from the tissues where CFTR is expressed
d. no change in susceptibility to cholera infection
e. decreased susceptibility to cholera infection
f. increased susceptibility to cholera infection
Answers: 1
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