Explain why mutations in COPI components build up proteins in the ER lumen. Mention specific proteins (besides COPI) in your answer.

the answer is cell division : )

for example, no new evidence will demonstrate that the earth does not orbit around the sun (heliocentric theory), or that living things are not made of cells (cell theory), that matter is not composed of atoms, or that the surface of the earth is not divided into solid plates that have moved over geological timescales .