Directions: Consider a pedigree that is tracking an autosomal recessive trait, where two recessive alleles (tt) result in the inability to taste a chemical known as PTC. The ability to taste PTC is determined by the presence of a
dominant allele (T). Complete the missing boxes in the chart. The first row has been done for you as an example!
Note: The ability to taste PTC may be more complex than a simple gene trait.
Individual Phenotype
Shaded?
PTC taster
Shape (in Pedigree)
Square
2.
No
1.
3.
4.
5.
6.
Male with genotype TT
Male with genotype Tt
Male with genotype tt
Female with genotype TT
Female with genotype Tt
Female with genotype tt
7.
8.
9.
10.
11.
12.
13.
14.
15.

Ms. w, a 21-year-old woman, came into a clinic after suffering a deep laceration on her foot while walking barefoot around her yard. the wound was cleaned, sutured, and bandaged, and she was released to return home after receiving tetanus antitoxoid. within 72 hours, the wound area was red and swollen, the suture line was dark in color, and it was accompanied by severe throbbing pain. ms. w had a high fever, her heart felt like it was racing, and she was finding it hard to concentraten even on simple tasks. she returned to the clinic and was immediately taken to the hospital. following lab tests, a diagnosis of acute necrotizing fasciitis was made. discussion questions 1. explain why ms. w. received a tetanus antitoxoid before leaving the hospital. (see chapters 3 and 4, infection and passive immunity.) 2. explain how acute necrotizing fasciitis developed in this case and the pathophysiology involved. (see acute necrotizing fasciitis.) 3. what is the potential outcome for ms. w if antibiotic drugs do not reduce the infection quickly?