RESPOND THOUGHTFULLY TO THIS DISCUSSION POST. The Question: How do the cellular proteins function (and coordinate) to accurately permit cell division? Describe at least one protein and its associated functions to support your answer.

The Person's Cellular proteins vary from being markers to forming rings that precede septation. They must coordinate by being active or inactive at a given time in the cell division process. For example, FtsZ is inactive in the cytoplasm while DNA replication is occurring. If it were active during this time, septation would occur prematurely. FTsZ forms the Z-ring which results in septum forming and thus septation.

Another example would be TipN. This protein marks the site of new poles in new cells and the location of the flagella. If this did not function, it would interfere with the overall shape of the new cells.

One of the most prominent features of tumor cells is uncontrolled cell proliferation caused by an abnormal cell cycle, and the abnormal expression of cell cycle-related proteins gives tumor cells their invasive, metastatic, drug-resistance, and anti-apoptotic abilities. Recently, an increasing number of cell cycle-associated proteins have become the candidate biomarkers for early diagnosis of malignant tumors and potential targets for cancer therapies. As an important cell cycle regulatory protein, Cell Division Cycle 25C (CDC25C) participates in regulating G2/M progression and in mediating DNA damage repair. CDC25C is a cyclin of the specific phosphatase family that activates the cyclin B1/CDK1 complex in cells for entering mitosis and regulates G2/M progression and plays an important role in checkpoint protein regulation in case of DNA damage, which can ensure accurate DNA information transmission to the daughter cells. The regulation of CDC25C in the cell cycle is affected by multiple signaling pathways, such as cyclin B1/CDK1, PLK1/Aurora A, ATR/CHK1, ATM/CHK2, CHK2/ERK, Wee1/Myt1, p53/Pin1, and ASK1/JNK-/38. Recently, it has evident that changes in the expression of CDC25C are closely related to tumorigenesis and tumor development and can be used as a potential target for cancer treatment. This review summarizes the role of CDC25C phosphatase in regulating cell cycle. Based on the role of CDC25 family proteins in the development of tumors, it will become a hot target for a new generation of cancer treatments.

Explanation:

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