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Biology, 24.04.2021 01:00 queenkimm26
The following schemes show the design of a peptide-based chemical probe and the proposed mechanism of its activity-based labeling of protein tyrosine phosphatase, an enzyme that is responsible for removing the phosphate from the tyrosine residue(s) of a peptide in a peptide-sequence specific manner. Based your understanding of the schemes and the relevant lecture material, identify the key structural components of this probe that are responsible for (a) binding, (b) covalently modifying, and (c) reporting, respectively.
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