Fibroblasts can be placed on thin sheets of silicone rubber. Under normal circumstances, fibroblasts exert sufficient tension on the rubber so that it visibly wrinkles. Explain how the ability of fibroblasts to wrinkle rubber would change if the cells were treated with a permeable form of C3 transferase, a toxin (from the bacterium Clostridium botulinum) that covalently modifies an amino acid in Rho. The modification renders Rho unable to bind to proteins that it would normally bind to when active.
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Fibroblasts can be placed on thin sheets of silicone rubber. Under normal circumstances, fibroblasts...
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