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Biology, 12.04.2021 20:50 milkshakegrande101

In the glycolytic pathway, the enzyme triose phosphate isomerase catalyzes the production of glyceraldehyde 3-phosphate (GAP) from dihydroxyacetone phosphate (DHAP). GAP continues through glycolysis via the reaction catalyzed by glyceraldehyde 3-phosphate dehydrogenase. In a muscle (myocyte) cell culture model, anaerobic conditions lead to cell death when triose phosphate isomerase is inhibited. In this same model, cells with inhibited triose phosphate isomerase survive under aerobic conditions. Briefly explain these findings including a discussion of energy production in anaerobic versus aerobic metabolism.

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