Metabolic acidosis can occur as a side effect of taking acetazolamide because: Select one: a. bicarbonate ions are wasted when sodium is excreted into the urine, leaving behind acidic metabolic waste products that need to be neutralized. b. chloride ions are wasted when sodium is excreted into the urine, leaving behind acidic metabolic waste products that need to be neutralized. c. bicarbonate ions are wasted when sodium is reabsorbed into the tubule as it attracts hydrogen ions. d. chloride ions are wasted when sodium is reabsorbed into the tubule as it attracts hydrogen ions.

a. bicarbonate ions are wasted when sodium is excreted into the urine, leaving behind acidic metabolic waste products that need to be neutralized.

Explanation:

Metabolic acidosis is an electrolyte disorder characterized by a pH of less than 7.40 and low bicarbonate (HCO3) levels in the blood. This disease may be due to 1-an increasing acid production, 2-loss of HCO3 (which acts as an acid buffer agent), and 3- by a decreasing ability of the kidneys to maintain normal acid levels. The kidneys contribute to maintaining the acid–base balance by excreting hydrogen ions (H+) into the urine and absorbing HCO3 from the urine. In metabolic acidosis, kidneys are unable to remove enough acid and conserve sodium ions (Na+), which is normally done by excreting ammonia in the urine.

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