1. What is apoptosis and what does it have to do with cancer cells? 2. What is the purpose of the Bcl‑2 proteins?

3. What is and oncogene and what can we gain from studying them?

1.Apoptosis in Cancer

The loss of apoptotic control allows cancer cells to survive longer and gives more time for the accumulation of mutations which can increase invasiveness during tumor progression, stimulate angiogenesis, deregulate cell proliferation and interfere with differentiation [2].

2.BCL-2 family proteins are the regulators of apoptosis, but also have other functions. This family of interacting partners includes inhibitors and inducers of cell death. Together they regulate and mediate the process by which mitochondria contribute to cell death known as the intrinsic apoptosis pathway.

3.

Explanation:

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