Which type of mutation often has the least effect on organisms' traits (and may have no effect at all)? Nondisjunction Substitution Insertion Deletion

The correct answer is - substitution.

Explanation:

Substitution mutations are the point mutations that are the mutations that least likely affect the trait of an organism or have no effect at all. Substitution mutations take place when there is only one nucleotide base is substituted by another nucleotide base in the  DNA or RNA of an organism's genome.

In this case, there is no effect found on the protein formed by these DNA sequences. These substitution mutations generally found in somatic cells and have little to no effect at all.

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the function of the protein macromolecule is to move things in and out of the cell and transport other molecules in the body. there are many functions of proteins. they are the basic building blocks of living things and are responsible for the growth and repair of body cells and tissues.

explanation: