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Hemostasis is the natural process that stops blood loss when an injury occurs. it involves three steps: (1) vascular spasm or vasoconstriction : (2) platelet plug formation and 3) coagulation . The platelet plug forms almost directly after a blood vessel has been ruptured. Within twenty seconds of an injury in which the blood vessel's epithelial wall is disrupted, coagulation is initiated and it takes only about sixty seconds until the first fibrin strands begin to intersperse among the wound. What step * (s) must be taken at the wound site for this plug formation to be initiated?
A. The clotting of a skin injury is caused by exposure to air, specifically oxygen, that activates platelet production.
B. Endothelial cells at the wound site stop secreting coagulation and aggregation inhibitors heparin and thrombomodulin
C. Clotting factors take part in a cascade of chemical reactions that eventually create a mesh of fibrin within the blood.
D. Thrombin is released to facilitate the conversion of the plasma protein called fibrinogen into long, insoluble fibers of the protein, fibrin
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Plz help me ASAP with this test question
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