How would you convert a spring into a straight piece of metal using the same approach as topoisomerase in DNA replication?

It would be necessary to make small breaks in the spring and then align the pieces, forming a straight piece.

Explanation:

Topoisomerase is the enzyme responsible for unwinding the DNA molecule during replication. To do this, topoisomerase makes small breaks in the DNA molecule, but uses covalent bonds to hold these small pieces of DNA, causing the strands of DNA to pass over each other, aligning in a rectilinear topography.

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the solute can move "downhill," from regions of higher to lower concentration, relying on the specificity of the protein carrier to pass through the membrane. this process is called passive transport or facilitated diffusion, and does not require energy.