Background information. There is a specialized protein called an enzyme that will convert pyruvate to acetyl-CoA, a key ingredient for the Krebs (citric acid) Cycle. The rate of pyruvate conversion is greatly reduced in individuals who do not have the enzyme to convert pyruvate into acetyl-CoA, a rare disorder.

Question.
Identify the location where the enzyme is most active.

pls help!!

Explanation:

Active site or catalytic site is the specific place in the enzyme where the substrate binds.

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