Tay-Sachs disease is a genetic disorder that results in the destruction of neurons due to a buildup of sphingolipids in the cells. Which organelle is malfunctioning in Tay-Sachs

Lysosomes

Explanation:

 Tay-sachs disease is a rare Autosomal recessive disease that causes neurodegenerative disorder.

Deficiency of  an enzyme Hexosaminidase A results in excessive accumulation of gangliosides (sialic acid containing glycosphingolipids) in the brain and nerve cells.

It is a lysosomal storage disease .Absence of  the enzyme Hexosaminidase A ,that breakdowns substance like fats results in accumulation of such substance in the lysosomes.Too much accumulation of fats in the lysosomes destroy the cell.

the denominator has a very specific role.

energy and particles