Activity #1 Normal DNA Sequence
DNA:
TAGTGCAT ATAT CATATAGCACT
mRNA:
Protein:
Mutated DNA Sequence
DNA:

mRNA:
Protein:
Describe the effects of the change(s) in the mutated DNA sequence. Did the protein change? Do you think
this protein can perform its normal function?
Stephanie Elkowitz
Help please

for the normal DNA sequence, since thymine (T) binds with adenine(A) and Adenine(A) binds with uracil(U) because there is no thymine is RNA guanine(G) pairs with cytosine(C) :

normal DNA:TAGTGCAT ATAT CATATAGCACT

normal mRNA:AUG GGG CAC GUA UAU AGU- AUA UCG UGA

i grouped letters in threes as codons

normal Protein:methionine-glycine-histidine-valine-Tyrosine-Serine-Isoleucine-serine-stop

 mutated DNA:

mutated mRNA:AUG GGG CAC GUG UAU AGC AUA UCG UGA

mutated protein:methionine-glycine-histidine-leucine-Tyrosine-Serine-Isoleucine-Serine-stop

In the mutated protein valine is replaced with leucine. Those two amino acids have different radicals that perform different functions so the protein will have an altered function.

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explanation: