In the early days of germ theory, contagious diseases were thought to be caused only by fungi or bacteria. In the 1890s, Dmitri Ivanovski filtered extracts from diseased tobacco plants and discovered that the disease could be transmitted to new plants through the filtrate. He hypothesized that something smaller than bacteria or fungi was responsible for the transmission of the disease. Which best explains how Ivanovski’s work led to a change in the germ theory?