Cells typically respond to DNA damage in three ways: by ceasing to grow and divide until the damage is repaired, by permanently ceasing to grow and divide, or by dying. In 2010 a group of scientists reported that a certain kind of immune reaction can cause DNA damage that leads to a fourth response. DNA damage can turn off genes involved in cell-signaling pathways. Turning off these genes can cause less-mature cells to divide too rapidly, often leading to the development of

Aperson with age is more likely to catch diseases that healthy people usually don’t catch.what are these infections called?

Ms. w, a 21-year-old woman, came into a clinic after suffering a deep laceration on her foot while walking barefoot around her yard. the wound was cleaned, sutured, and bandaged, and she was released to return home after receiving tetanus antitoxoid. within 72 hours, the wound area was red and swollen, the suture line was dark in color, and it was accompanied by severe throbbing pain. ms. w had a high fever, her heart felt like it was racing, and she was finding it hard to concentraten even on simple tasks. she returned to the clinic and was immediately taken to the hospital. following lab tests, a diagnosis of acute necrotizing fasciitis was made. discussion questions 1. explain why ms. w. received a tetanus antitoxoid before leaving the hospital. (see chapters 3 and 4, infection and passive immunity.) 2. explain how acute necrotizing fasciitis developed in this case and the pathophysiology involved. (see acute necrotizing fasciitis.) 3. what is the potential outcome for ms. w if antibiotic drugs do not reduce the infection quickly?

You are studying a protein that you call protein x. there is an aspartic acid at a key position in protein x which is important in the folding and stabilization of that protein. if this aspartic acid is changed to a different amino acid, which type of amino acid substitutions is most likely to allow the protein to fold normally?