Which statement best explains how mutations change the shape of flu virus antigens, preventing the attachment of antibodies? A. Mutations change the nucleotide sequence of the gene, resulting in a different arrangement of amino acids.

B. Mutations change the amino acid sequence of the protein, resulting in a change in the nucleotide sequence

C. Mutations cause overproduction of new antigens on the surface of the virus.

D. Mutations allow for the exchange of antigens among virus species.

A. Mutations change the nucleotide sequence of the gene, resulting in a different arrangement of amino acids.

Explanation:

Mutations alter the sequence of nucleotides in a molecule of DNA. DNA is used to create mRNA, which is used to create a chain of amino acids that make a protein. If the mutation changes the sequence of DNA, then the sequence of amino acids and the final protein will be different.

This can affect its structure and function. If the protein is a cell surface protein, and its structure is significantly altered, antibodies may no longer recognise and bind to the protein.