A single base-pair mutation occurs in a promoter sequence of a gene. As a result of the mutation, what are the possible effects on the transcription level of the gene?

This mutation could increase, reduce, have no effect, or even eliminate the transcriptional activity

Explanation:

A single pair mutation (also known as point mutation) is caused when only one nucleotide in the DNA sequence is changed. A promoter is a DNA sequence that binds to the RNA polymerase and transcription factors in order to initiate the transcription. When a point mutation results in a promoter region, this may alter transcription, and its effects can be determined by measuring the level of gene transcription. In a promoter bashing assay, point mutations are generated in the promoter region in order to determine their effects on gene expression.

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-lavira: )

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