Which is a true statement regarding metastasis? Increased cell-to-cell adhesion helps metastasis. Lack of proteases and collagenases aids in metastasis. Cells must first escape the basement membrane of tissue. Penetration of the basement membrane of the vessel occurs first.

The correct answer to the question is option C

CELLS MUST FIRST ESCAPE THE BASEMENT MEMBRANE OF TISSUES.

Explanation: For any tumour cell to be able to gain entry into the lymphatic circulation or into the blood,there must first be an escape of the tumour cell from the basement membrane of the tissue it originated from,when the tumor first moves out if the basement membrane,it further moves through the extracellular space and then finds its way to the basement membrane of the vessel.

Spread of the tumour cells from it's point of origin (metastasis) is thought to involve the loss of cell to cell adhesion proteases and collagenases digestion of the basement membrane.

The basement membrane of the vessel can only be penetrated only if and after the basement membrane of the affected organ has been affected/breached.

succession returns a disturbed

ecosystem to a more stable state. this is also classified into two (2) types:

primary succession and secondary succession. the primary succession arises when

a new land is transformed and a bare rock has been exposed providing an environment

that can be occupied for the first time. while, secondary succession occurs

when a previously occupied environment was disturbed that kills much of all its

community

explanation: