Manifestations of osteoarthritis include ( Select all that apply.) nodules on joints of the hands. crepitus with joint movement. pain that is worse upon arising in the morning. stiffness that worsens with joint use. narrowing of joint spaces

All options are correct, that is, they would all be correct for osteoarthritis.

This disease is characterized by being very painful at the joint level, it is degenerative, and mobility decreases over time.

Explanation:

Osteoarthritis is a pathology that is based on the fegenerative destruction of the joints, generating edema and loss of function, that is why it is pain.

The pain is very intense and very marked, that is why it is treated with immunosuppressive drugs and analgesics. (In addition to kinesiology and physiotherapy).

This disease decreases the functional unit and the joint space, generating possible ankylosis, pseudoarthrosis, elimination of lubricating fluid from joints and nodular structures. These nodular structures tend to be more common in the hands and are called by professionals as "drum fingers".

a tetrad is the foursome during meiosis made by two homologous chromosomes that have each already replicated into a pair of sister chromatids.

the median of the data is 4.5.